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pMEV2HA-AKT1-AA

https://www.e-scapebio.com/web/image/product.template/621299/image_1920?unique=6d46103
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pMEV2HA-AKT1-AA is a high-quality, expression-ready plasmid encoding a dominant-negative mutant of human AKT1, where key phosphorylation sites Thr308 and Ser473 are substituted with alanine (T308A/S473A). This dual mutation renders the AKT1 protein inactive, preventing activation by upstream kinases, making it a powerful tool for studying AKT1 signaling pathways, apoptosis regulation, and growth factor response. Expressed under the pMEV2 promoter with an N-terminal HA tag for easy detection, this clone is ideal for transfection into mammalian cells to suppress endogenous AKT1 activity and analyze phosphorylation-dependent cellular processes. - 20 ug

583.08 € 583.08 EUR 583.08 € Tax Excluded

583.08 € Tax Excluded

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This kit is an essential tool for professionals seeking to conduct detailed analyses of neurotransmitter levels in urine, aiding in the understanding and management of various neurological and psychiatric conditions.

 
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Internal Reference: GEN - BXA1010-aa
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