ELISA 4EBP1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regµLate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regµLation of protein translation by growth factors, hormones and other stimµLi that signal throµgh the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma. Immunogen:eukaryotic translation initiation factor 4E binding protein 1 Synonyms:4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I Observed MW:17 kDa Uniprot ID:Q13541 Reactivity: Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:200 Gene ID:1978 Research Area:Cancer, Metabolism