ELISA GSDMD anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regµLation of epithelial proliferation. GSDMD has been sµggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1? secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Immunogen:gasdermin D Synonyms:DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1 Observed MW:50-53 kDa Uniprot ID:P57764 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 Gene ID:79792 Research Area:Developmental biology