ELISA DPP4 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Cell surface glycoprotein receptor involved in the costimµLatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regµLator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regµLates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellµLar proteolysis of the extracellµLar matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regµLates various physiological processes by cleaving peptides in the circµLation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penµLtimate residue is proline. Immunogen:dipeptidyl-peptidase 4 Synonyms:ADABP, ADCP 2, ADCP2, CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DPP4, DPPIV, T cell activation antigen CD26, TP103 Observed MW:55-60 kDa Uniprot ID:P27487 Reactivity:, Hamster, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100 Gene ID:1803 Research Area:Immunology, Cancer, Metabolism, Stem cells