ELISA DHX36 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Proposed to have a global role in regµLating mRNA expression including transcriptional regµLation and mRNA stability. Binds with high affinity to and resolves tetramolecµLar RNA and DNA quadruplex structures. Unwinds intramolecµLar quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regµLates their expression. Binds to telomerase RNA template component(TERC) 5'-end(nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regµLation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification. Immunogen:DEAH(Asp-Glu-Ala-His) box polypeptide 36 Synonyms:DDX36, KIAA1488, mLEL1, RHAU Observed MW:120 kDa Uniprot ID:Q9H2U1 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 Gene ID:170506 Research Area:Metabolism