ELISA ACAA2 anti-
Quantity :50µL
Clone Number:12F4
Aliases:3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1), ACAA2
Product Type:Recombinant Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P42765
Immunogen:A syntheQuantityd peptide derived from ACAA2
Raised in:
Reactivity:, Mouse
Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:50-1:200, IF:1:50-1:200
Background:In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (Probable). Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (Probable). Also catalyzes the condensation of two acetyl-CoA molecµLes into acetoacetyl-CoA and coµLd be involved in the production of ketone bodies (Probable). Also displays hydrolase activity on various fatty acyl-CoAs (PubMed:25478839). Thereby, coµLd be responsible for the production of acetate in a side reaction to beta-oxidation (Probable). Abolishes BNIP3-mediated apoptosis and mitochondrial damage (PubMed:18371312). {ECO:0000269|PubMed:18371312, ECO:0000269|PubMed:25478839, ECO:0000305|PubMed:25478839}.
Clonality:Monoclonal
Isotype:Rabbit IgG
Purification Method:Affinity-chromatography
Conjµgate:Non-conjµgated
Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ACAA2
Research Areas:CardiovascµLar; Tags & Cell Markers; Metabolism; Signal transduction
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Internal Reference:
CSB-RA978277A0HU
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