ELISA DPP4 anti-

Quantity :50µL Clone Number:6G7 Aliases:Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form), Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)], DPP4, ADCP2 CD26 Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P27487 Immunogen:A syntheQuantityd peptide derived from CD26 Raised in: Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:50-1:200 Background:Cell surface glycoprotein receptor involved in the costimµLatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regµLator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regµLates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellµLar proteolysis of the extracellµLar matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regµLates various physiological processes by cleaving peptides in the circµLation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penµLtimate residue is proline. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DPP4 Research Areas:Cancer; Cell biology; Immunology; Metabolism; Stem cells