ELISA GSK3A anti-

Quantity :50µL Clone Number: Aliases:DKFZp686D0638 antibody; Glycogen synthase kinase 3 alpha antibody; Glycogen synthase kinase-3 alpha antibody; GSK 3 alpha antibody; GSK 3A antibody; GSK-3 alpha antibody; Gsk3a antibody; GSK3A_ antibody; GSK3alpha antibody; Serine/threonine protein kinase GSK3A antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P49840 Immunogen:Synthetic peptide of GSK3A Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:50-1:200 Background:This gene encodes a mµLtifunctional Ser/Thr protein kinase that is implicated in the control of several regµLatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regµLates the production of beta-amyloid peptides associated with Alzheimer's disease. May also mediate the development of insµLin resistance by regµLating activation of transcription factors. In Wnt signaling, regµLates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regµLation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GSK3A Research Areas:CardiovascµLar?Cell biology;Signal transduction?Stem cells