ELISA DHH anti-

Quantity :50µL Clone Number: Aliases:C78960 antibody; Desert hedgehog (Drosophila) homolog antibody; Desert hedgehog antibody; Desert hedgehog homolog (Drosophila) antibody; Desert hedgehog protein C-product antibody; Desert hedgehog protein precursor antibody; DHH antibody; DHH_ antibody; GDXYM antibody; HHG-3 antibody; Hira antibody; SRXY7 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43323 Immunogen:Synthetic peptide of DHH Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecµLes that play an important role in regµLating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throµghout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicµLar polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DHH Research Areas:Stem cells