ELISA DKK4 anti-

Quantity :50µL Clone Number: Aliases:Dickkopf 4 antibody; Dickkopf gene 4 antibody; Dickkopf homolog 4 (Xenopus laevis) antibody; Dickkopf homolog 4 antibody; Dickkopf related protein 4 antibody; Dickkopf-4 antibody; Dickkopf-related protein 4 short form antibody; Dickkopf4 antibody; DKK 4 antibody; Dkk-4 antibody; DKK4 antibody; DKK4_ antibody; hDkk 4 antibody; hDkk-4 antibody; hDkk4 antibody; MGC129562 antibody; MGC129563 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UBT3 Immunogen:Recombinant Dickkopf-related protein 4 protein (19-224AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regµLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adµLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DKK4 Research Areas:Stem cells