ELISA DIS3L2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:DI3L2_ antibody; DIS3 L2 antibody; DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody; DIS3 mitotic control homolog like 2 antibody; DIS3-like exonuclease 2 antibody; Dis3l2 antibody; FLJ36974 antibody; MGC42174 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IYB7 Immunogen:Recombinant DIS3-like exonuclease 2 protein (201-400AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regµLates cell proliferation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DIS3L2 Research Areas:Cell biology