ELISA DOK2 (Ab-299) anti-

Quantity :100µL Clone Number: Aliases:Docking protein 2 56kDa antibody; Docking protein 2 antibody; DOK 2 antibody; DOK R antibody; DOK2 antibody; DOK2_ antibody; Downstream of tyrosine kinase 2 antibody; OTTHUMP00000161710 antibody; OTTHUMP00000224923 antibody; p56(dok 2) antibody; p56(dok-2) antibody; p56dok 2 antibody; p56DOK antibody; p56dok2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O60496 Immunogen:Peptide sequence around aa.297~301 (G-E-Y-A-V) derived from p56Dok-2. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 Background:DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of mµLtimolecµLar signaling complexes. DOK2 may modµLate the cellµLar proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modµLating Bcr-Abl signaling. Attenuates EGF-stimµLated MAP kinase activation Feng Cong, et,al. (1999) Mol. Cell. Biol; 19: 8314 - 8325. Serge Lemay, et,al. (2000) Mol. Cell. Biol; 20: 2743 - 2754. Ute Schaeper, et,al.(2000) J. Cell Biol; 149: 1419. Miyuki Honma, et,al. (2006) Genes Cells; 11: 143 - 151. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DOK2 Research Areas:Cancer;Signal transduction