ELISA ABCC2 anti-

Quantity :50µL Clone Number: Aliases:ABC30 antibody; abcC2 antibody; ATP binding cassette sub family C (CFTR/MRP) member 2 antibody; ATP binding cassette subfamily C member 2 antibody; ATP-binding cassette sub-family C member 2 antibody; CanalicµLar mµLtidrµg resistance protein antibody; CanalicµLar mµLtispecific organic anion transporter 1 antibody; CMOAT antibody; CMOAT1 antibody; cMRP antibody; DJS antibody; KIAA1010 antibody; MRP 2 antibody; MRP2_ antibody; MµLtidrµg resistance associated protein 2 antibody; MµLtidrµg resistance-associated protein 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92887 Immunogen:Synthetic peptide of ABCC2 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:30-1:150 Background:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecµLes across extra- and intra-cellµLar membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in mµLti-drµg resistance. This protein is expressed in the canalicµLar (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drµgs such as vinblastine; therefore, this protein appears to contribute to drµg resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjµgated hyperbilirubinemia. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ABCC2 Research Areas:Cancer;Metabolism;Signal transduction