ELISA DNAJA1 anti-

Quantity :50µL Clone Number: Aliases:DJ 2 antibody; DJ2 antibody; DjA1 antibody; DnaJ (Hsp40) homolog; subfamily A; member 1 antibody; DnaJ homolog subfamily A member 1 antibody; DnaJ protein homolog 2 antibody; DNAJ2 antibody; Dnaja1 antibody; DNJA1_ antibody; hDJ 2 antibody; HDJ-2 antibody; HDJ2 antibody; Heat shock 40 kDa protein 4 antibody; heat shock protein DNAJ like 2 antibody; Heat shock protein J2 antibody; HSDJ antibody; HSJ-2 antibody; HSJ2 antibody; HSPF4 antibody; DnaJ protein 2 antibody; NEDD7 antibody; Neural precursor cell expressed developmentally down regµLated 7 antibody; OTTHUMP00000021193 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P31689 Immunogen:Fusion protein of DNAJA1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 Background:DnaJ-like proteins interact with HSP 70 molecµLar chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellµLar redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regµLate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simµLtaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNAJA1 Research Areas:Signal transduction