ELISA GREM1 anti-

Quantity :50µL Clone Number: Aliases:BMP antagonist 1 antibody; Cell proliferation inducing gene 2 protein antibody; Cell proliferation-inducing gene 2 protein antibody; CKTSF1B1 antibody; colorectal adenoma and carcinoma 1 antibody; Cysteine knot superfamily 1 antibody; Cysteine knot superfamily 1; BMP antagonist 1 antibody; Cysteine knot superfamily BMP antagonist 1 antibody; DAN domain family member 2 antibody; DAND2 antibody; Down regµLated in Mos-transformed cells protein antibody; Down-regµLated in Mos-transformed cells protein antibody; DRM antibody; grem1 antibody; GREM1_ antibody; GremLin 1 homolog; cysteine knot superfamily antibody; GremLin 1 like protein antibody; GremLin 1; cysteine knot superfamily; homolog antibody; GREmLIN antibody; GremLin-1 antibody; GremLin1 antibody; IHG-2 antibody; IHG2 antibody; Increased in high glucose 2 antibody; Increased in high glucose protein 2 antibody; PIG2 antibody; Proliferation inducing gene 2 antibody; proliferation inducing gene 2 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O60565 Immunogen:Fusion protein of GREM1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000 Background:This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regµLating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GREM1 Research Areas:Signal transduction?Stem cells