ELISA ANLN anti-

Quantity :50µL Clone Number: Aliases:Actin binding protein scraps homolog Drosophila antibody; Actin binding protein anillin antibody; Actin-binding protein anillin antibody; Anillin actin binding protein antibody; anln antibody; ANLN_ antibody; DKFZp779A055 antibody; FSGS8 antibody; Scra antibody; Scraps antibody; Scraps homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NQW6 Immunogen:Fusion protein of ANLN Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background: Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ANLN Research Areas:Cell biology;Signal transduction