ELISA GRPR anti-

Quantity :50µL Clone Number: Aliases:BB2 antibody; Bombesin BB2 receptor antibody; bombesin receptor 2 antibody; Gastrin Releasing Peptide Receptor antibody; Gastrin-releasing peptide receptor antibody; GRP preferring bombesin receptor antibody; GRP R antibody; GRP-preferring bombesin receptor antibody; GRP-R antibody; Grp/bombesin receptor antibody; Grpr antibody; GRPR_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P30550 Immunogen:Synthetic peptide of GRPR Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 Background:Gastrin-releasing peptide (GRP) regµLates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated throµgh the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and mµLtiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GRPR Research Areas:Neuroscience;Signal transduction