ELISA DPP4 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:ADABP antibody; ADCP-2 antibody; ADCP2 antibody; Adenosine deaminase complexing protein 2 antibody; CD26 antibody; Dipeptidyl peptidase 4 antibody; Dipeptidyl peptidase 4 soluble form antibody; Dipeptidyl peptidase IV antibody; Dipeptidyl peptidase IV membrane form antibody; Dipeptidyl peptidase IV soluble form antibody; DPP IV antibody; DPP4 antibody; DPP4_ antibody; DPPIV antibody; T-cell activation antigen CD26 antibody; TP103 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P27487 Immunogen:Recombinant Dipeptidyl peptidase 4 protein (473-588AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Cell surface glycoprotein receptor involved in the costimµLatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regµLator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regµLates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellµLar proteolysis of the extracellµLar matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regµLates various physiological processes by cleaving peptides in the circµLation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penµLtimate residue is proline. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DPP4 Research Areas:Cancer; Cell biology; Immunology; Metabolism; Stem cells