ELISA DKK1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Dickkopf 1 antibody; Dickkopf 1 homolog antibody; Dickkopf 1 like antibody; Dickkopf homolog 1 antibody; Dickkopf like protein 1 antibody; Dickkopf related protein 1 antibody; Dickkopf WNT signaling pathway inhibitor 1 antibody; Dickkopf-1 antibody; Dickkopf-related protein 1 antibody; DKK 1 antibody; Dkk-1 antibody; Dkk1 antibody; DKK1_ antibody; hDkk 1 antibody; hDkk-1 antibody; SK antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O94907 Immunogen:Recombinant Dickkopf-related protein 1 protein (33-266AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regµLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adµLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DKK1 Research Areas:CardiovascµLar; Developmental biology; Immunology; Stem cells