ELISA DOK1 anti-

Quantity :50µL Clone Number: Aliases:Docking protein 1 62kD antibody; Docking protein 1 antibody; DOK 1 antibody; DOK1 antibody; DOK1_ antibody; Downstream of tyrosine kinase 1 antibody; p62(dok) antibody; P62DOK antibody; pp62 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q99704 Immunogen:Fusion protein of DOK1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000 Background:The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of mµLtiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regµLator of the insµLin signaling pathway. ModµLates integrin activation by competing with talin for the same binding site on ITGB3. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DOK1 Research Areas:Cancer?CardiovascµLar;Metabolism;Signal transduction