ELISA GRB7 anti-

Quantity :50µL Clone Number: Aliases:B47 antibody; Epidermal growth factor receptor GRB 7 antibody; Epidermal growth factor receptor GRB-7 antibody; GRB7 adapter protein antibody; GRB7 antibody; GRB7_ antibody; Growth factor receptor bound protein 7 antibody; Growth factor receptor-bound protein 7 antibody; OTTHUMP00000164349 antibody; OTTHUMP00000164350 antibody; OTTHUMP00000164351 antibody; OTTHUMP00000164352 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14451 Immunogen:Recombinant Growth factor receptor-bound protein 7 protein (233-532AA) Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 Background:Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modµLates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regµLation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granµLes. Binds to the 5\\\'UTR of target mRNA molecµLes and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granµLe disassembly during recovery after cellµLar stress (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GRB7 Research Areas:Signal transduction