ELISA GRB14 Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:GRB14Growth factor receptor-bound protein 14 antibody; GRB14 adapter protein antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q14449
Immunogen:Recombinant Growth factor receptor-bound protein 14 protein (294-397AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:Adapter protein which modµLates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insµLin receptor (INSR). Potent inhibitor of insµLin-stimµLated MAPK3 phosphorylation. Plays a critical role regµLating PDPK1 membrane translocation in response to insµLin stimµLation and serves as an adapter protein to recruit PDPK1 to activated insµLin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insµLin signal.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GRB14
Research Areas:Signal transduction
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Internal Reference:
CSB-PA009888LC01HU
Website URL:
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