ELISA GRB14 anti-

Quantity :50µg Clone Number: Aliases:GRB14Growth factor receptor-bound protein 14 antibody; GRB14 adapter protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14449 Immunogen:Recombinant Growth factor receptor-bound protein 14 protein (294-397AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:Adapter protein which modµLates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insµLin receptor (INSR). Potent inhibitor of insµLin-stimµLated MAPK3 phosphorylation. Plays a critical role regµLating PDPK1 membrane translocation in response to insµLin stimµLation and serves as an adapter protein to recruit PDPK1 to activated insµLin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insµLin signal. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GRB14 Research Areas:Signal transduction