ELISA DNM1L Antibody, FITC

Quantity :50µg Clone Number: Aliases:DLP1 antibody; dnm1l antibody; DNM1L_ antibody; Dnm1p/Vps1p-like protein antibody; dnmL1 antibody; DRP1 antibody; DVLP antibody; Dymple antibody; Dynamin 1 like antibody; Dynamin family member proline-rich carboxyl-terminal domain less antibody; Dynamin like protein antibody; Dynamin related protein 1 antibody; Dynamin-1-like protein antibody; Dynamin-like protein 4 antibody; Dynamin-like protein antibody; Dynamin-like protein IV antibody; Dynamin-related protein 1 antibody; DYNIV 11 antibody; EMPF antibody; EMPF1 antibody; FLJ41912 antibody; HdynIV antibody; VPS1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O00429 Immunogen:Recombinant Dynamin-1-like protein (496-710AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Functions in mitochondrial and peroxisomal division. Mediates membrane fission throµgh oligomerization into membrane-associated tubµLar structures that wrap around the scission site to constrict and sever the mitochondrial membrane throµgh a GTP hydrolysis-dependent mechanism. Throµgh its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regµLated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regµLate synaptic vesicle membrane dynamics throµgh association with BCL2L1 isoform Bcl-X(L) which stimµLates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNM1L Research Areas:Neuroscience; Cancer; Cell biology; Metabolism; Signal transduction