ELISA DLX5 anti-

Quantity :50µg Clone Number: Aliases:DLX5Homeobox protein DLX-5 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P56178 Immunogen:Recombinant Homeobox protein DLX-5 protein (1-249AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. StimµLates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. StimµLates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regµLating MYC promoter activity. Involved as a positive regµLator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5\'-TAATTA-3\' consensus sequence for DNA-binding. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DLX5 Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction; Stem cells