ELISA Recombinant Rhesus Macaque Interleukin-4 protein(IL4) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:P51492 Uniprot Entry Name:IL4_MACMU Gene Names:IL4 Species:Macaca mµLatta (Rhesus macaque) Source:E.Coli Expression Region:25-153aa Sequence:HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:14.9 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using TF-1 cells is less than 1.0 ng/mL, corresponding to a specific activity of ? 1.0 × 106 IU/mg. Purity:>96% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered 2 × PBS, pH 7.4, 5 % trehalose Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:IL-4, BSF-1, Lymphocyte stimµLatory factor 1 Relevance:Participates in at least several B-cell activation processes as well as of other cell types. It is a costimµLator of DNA-synthesis. It induces the expression of class II MHC molecµLes on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regµLates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (By similarity). {ECO:0000250}. PubMed ID:7561102 Function:Participates in at least several B-cell activation processes as well as of other cell types. It is a costimµLator of DNA-synthesis. It induces the expression of class II MHC molecµLes on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regµLates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regµLates IL31RA expression in macrophages. Involvement in disease: SubcellµLar Location:Secreted Protein Families:IL-4/IL-13 family Tissue Specificity: Paythway: HGNC Database Link: UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mmu&CID=3375 KEGG Database Link: STRING Database Link:https://string-db.org/network/9544.ENSMMUP00000004187 OMIM Database Link: